18 March 2020

Nautilus Magazine: Natural Selection in an Outbreak

Ebola doesn’t select people. We haven’t figured out what Ebola virus selects as its natural host, but it’s definitely not humans. Every once in a while, Ebola stumbles upon a human host, which ends up being a fatal mistake. When I say fatal, I mean for the virus. After all, Ebola is usually not highly efficient at sustaining infection or transmitting from human to human, and eventually that chain of transmission turns into a dead end. Every Ebola outbreak has ended, even the 2014-2015 West African epidemic. [...]

The circumstances that favor Ebola spillover to humans aren’t necessarily the same ones that drive full-scale epidemics, and it’s important to understand this distinction. Natural selection is the process by which the environment dictates what will thrive. Normally, a human population is not a hospitable environment for Ebola virus. But when we have dysfunctional healthcare systems, we convert a dead-end spillover event into a large outbreak—we select Ebola. It’s no coincidence that the largest Ebola outbreaks occurred in countries with weak governments recovering from brutal civil unrest, with poor education systems and inadequate healthcare infrastructures. Ebola virus finds succor in environments where hepatitis B is uncontrolled and cholera regularly sweeps through. It’s the environments where healthcare systems lag behind rapidly growing urban populations, where road networks carry natural resources out of remote areas but medical supplies cannot find their way in, and where everyone with a fever is told they have “malaria/typhoid” because there are no laboratory facilities to tell them otherwise. It’s these human environments that select Ebola. [...]

There’s a lot of speculation about what dampens and ultimately ends an Ebola outbreak. When a spillover turns into an epidemic turns into a trickle of cases, credit goes to the highly technical international response of laboratories and treatment units, skilled local surveillance and monitoring teams, and even the increasing numbers of survivors that cannot be re-infected. What is often missing from the discussion is how communities adapted to this new threat. How they altered their environment through the use of improvised protective equipment and self- or locally-imposed quarantine. We can all learn from this resilience and resourcefulness. It is this local adaption and memory that we will depend upon, if we as a global community fail to build up the failing healthcare systems that favor Ebola.

17 March 2020

UnHerd: Will coronavirus change the world?

Epidemics have been around as long as civilization. Plaga — from the Greek for ‘strike’ or ‘hit’ — devastated classical Athens in the 5th century BC, when the historian Thucydides nursed sufferers; the Antonine Plague — probably smallpox or measles — killed as many as five million Romans at the empire’s peak. Far more deadly was the Plague of Justinian in the sixth century, which had a toll of 25 million and emptied whole regions of the eastern (Byzantine) Empire. Only in the 21st century did researchers confirm that this was the same illness that would appear eight centuries later — the Bubonic Plague. [...]

Another danger is climate change, which might turn a mild virus into a deadly one, or cause disease-carrying animals to migrate. This is what happened during the 14th century when the northern hemisphere became considerably cooler, soon after the Mongols had created the largest contiguous empire in history. [...]

In contrast, Milan perhaps had higher survival rates, because its rulers, the ruthless Visconti family, ordered that any house where the plague was identified be boarded up and its inhabitants left to starve. In a later outbreak the city of Dubrovnik, now in Croatia, initiated the rule that all ships stay anchored for 40 days — quaranta — a sensible measure that appreciated the potential length of incubation periods. [...]

Contagious diseases historically raised fear of the outgroup, and already we have seen low-level violence against east Asians in Italy. We’re not going to get pogroms now, partly because children are largely unaffected — the fatality rate for the 0-9s in China still 0 per cent of the 416 confirmed cases —and that’s what really drives terror, but plagues do draw out our most atavistic fears. There is a theory that xenophobia is an evolutionary response to pathogens, since strangers are more likely to carry diseases that the in-group has no immunity to, and that’s why conservatives respond more strongly to disgust and value purity and cleanliness.

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Social Europe: How the new EU gender strategy fails east-central European women

The premise of the strategy is that gender equality is ‘an essential condition for an innovative, competitive and thriving European economy’, which ‘brings more jobs and higher productivity’. This is in line with what has historically driven the EU to legislate on equality between the sexes—the desire not to eradicate inequalities but to optimise the performance of the labour market by ensuring a steady supply of workers. Indeed, one of the key indicators through which the progress towards gender equality in EU member states is measured is the (increasing) proportion of women in the labour market. What this refuses to consider however, are the labour conditions which women are encouraged to enter.

As we have seen in east-central Europe, this experience has been far from emancipatory for many women, as a large proportion of the jobs created in the past three decades have been of poor quality: underpaid, low-skilled, socially undervalued and performed on zero-hours contracts. Kováts and Gregor showed in their research on Hungarian women that broad segments feel so exploited in the labour market that, rather than think how to escape home to do meaningful work and secure financial independence, their main concern is how to escape employment to be with their loved ones. This exposes the hollowness of the commission’s equation of gender equality with more women on the labour market, as at best out of touch and at worst wilfully class-blind. [...]

The narrow neoliberal framework through which the strategy challenges gender inequalities in the supply of care work is also evident in its focus on solving growing demand by encouraging (individual) men to take it up, as well as establishing institutions relieving women of these responsibilities. While both are certainly necessary, they are woefully inadequate to address the deeper underlying tension within capitalist societies—the need for reproductive labour to sustain productive labour, with the associated lack of valorisation and remuneration. Unless we fundamentally restructure ‘worker’ and ‘carer’ roles deemed separate and mutually exclusive, we cannot hope to eradicate this tension, no matter what work-life balance efforts we apply.

Social Europe: Covid-19 is an opportunity for Europe

The Covid-19 epidemic is not just any stress test. For starters, it is likely to affect the entire world, leading to a synchronised growth slowdown or even recession. Synchronised recessions are virtually always deeper and longer-lasting than downturns affecting individual economies, and they hit open economies such as the EU particularly hard.

Compounding the problem, because every EU member state is facing a severe shock, they will be far less able to help one another than they were during the eurozone crisis that began in 2010. To be sure, Italy has suffered the most so far. But past transmission patterns elsewhere suggest that Covid-19 will continue to spread across Europe, putting every country under growing strain. [...]

The Covid-19 pandemic thus represents an opportunity for the EU to create a powerful crisis-management mechanism, which pools member states’ resources and channels them toward a co-ordinated fiscal policy. The idea of such an ‘insurance fund’ is not new: several economists championed the idea after the last crisis, when discussion of governance reform was in full swing.

Nautilus Magazine: The Man Who Saw the Pandemic Coming

Typically the preparation of the animal is where you have exposure. By the time it’s cooked and prepared, the virus would have been dead. It’s more common that transmission is through the animal shedding or people slaughtering the animal, when they’re exposed to bodily fluids, blood, and secretions. With the avian influenza from poultry, a lot of the exposure and infections go back to the preparation of chicken for cooking. In Egypt, for instance, when you look at who was infected, more common than not it was a woman, directly responsible for slaughtering and preparing the animal. [...]

Certainly. We’ve been able to identify bats as reservoirs for coronaviruses and documented specific bat populations as reservoirs for Ebola virus. We want to understand how each of these bats operate within an ecosystem. Do they have certain behaviors and practices that either keep them remote from or proximal to human populations? The bat population in which we isolated the Ebola virus in West Africa was a species of bat that also tends to co-roost within human housing, so it elevates the opportunity for spillover. [...]

Yes. EcoHealth Alliance, an NGO, and others, looked at all reported outbreaks since 1940. They came to a fairly solid conclusion that we’re looking at an elevation of spillover events two to three times more than what we saw 40 years earlier. That continues to increase, driven by the huge increase in the human population and our expansion into wildlife areas. The single biggest predictor of spillover events is land-use change—more land going to agriculture and more specifically to livestock production. [...]

Oh, sure. It was predictable. It’s like if you had no traffic laws and were constantly finding pedestrians getting whacked by cars as they crossed the street. Is that surprising? No. All you need to do is to better manage how we set up crosswalks, how we establish traffic rules and regulations. We’re not doing that. We’re not establishing the kind of safe practices that will minimize the opportunity for spillover. If we better understood where these viruses are circulating and understood that ecology, we would have the potential to disrupt and minimize the risk of spillover.